The following article mentions eating disorders.
Here are 31 stars who look different after taking Ozempic and other weight-loss drugs.
The actor’s “year of health” involved a number of changes, including losing around 80 pounds.

“It wasn’t a goal to get to a certain weight.
“There are people that just have no ‘off’ button to eat, right?”
However, he wasn’t totally on board with this move at first.

“I’m just grateful because it’s such a better life,” he toldPeople.
I’m just a fat guy trying to not die.”
Kelly Clarkson
Superstar singer and talk show host Kelly Clarkson resisted using weight loss medication for years.

“Everybody thinks it’s Ozempic.
Clarkson’s weight-loss journey has been a long road.
In 2018, for example, she lost 37 pounds after cutting lectins from her diet.

“For me, it was ‘I’m not on my medicine any more.'”
In 2024, she toldPeoplethat sticking to a protein-heavy diet and walking regularly also helped her lose weight.
Musk has, however, been a vocal proponent of all these weight-loss drugs doing rounds in celebrity circles.

The most obvious conclusion people drew pointed toward Ozempic.
“It’s very hard to say you’ve had enough.”
It was a diabetes diagnosis that drove Bates to make some changes.

“[Diabetes] runs in my family, and I’d seen what my father had gone through.
He had had a leg amputation.
One of my sisters is dealing with it very seriously, and it terrified me.

It scared me straight,” she said.
“I just pushed the plate away.”
Oprah Winfrey
When Oprah Winfrey signs off on something, it is bound to grab widespread attention.

Winfrey has also been candid about the stigma surrounding using certain medications for weight loss.
Zepbound, like Mounjaro, is a brand of tirzepatide.
The “Mrs. Doubtfire” actor has struggled with his weight for decades.

At his heaviest, he weighed over 300 pounds.
“I’ve been skinny before, that’s the sad part.
After gaining weight during the pandemic, Fierstein turned to Zepbound.

“People don’t understand that being fat is not a choice.
It’s something that you’re body is out of whack and this puts your body in whack.”
Newsin 2023, saying that the bang out 2 diabetes medication helped her drop 30 pounds.

“Whatever you choose is up to you,” she stated.
She eventually ended up losing 42 pounds on the drug.
“Ozzy’s having a go at me because he says I look like Mrs. Reagan.

He calls me Nancy Reagan all the time!
So it’s just time to stop,” she said on"Piers Morgan Uncensored.
“She quit using Ozempic in 2023.

“That was the only way they could jumpstart my system … By the end of the year, Goldberg was proudly showing off her transformed physique on her show.
“My doctor told me, she says, there’s a lot of fat young people.
“It cuts my appetite in half.

Now I only eat half a bag of Doritos,” he toldE!
Newsin 2024, further detailing that he took the diabetes medicine once a week.
His comment gained widespread attention, though the humor of it was lost in his straight-faced delivery of it.

Spelling was 44 when her youngest son was born.
“I did Mounjaro and everyone admits it now.
It’s a different time so I don’t feel shamed saying that,” she said.

The reality star was also given hormonal prescriptions along with the diabetes medicine.
After reaching her desired weight, Spelling stopped using Ozempic in early 2024.
The regret of not starting it 10 years ago.”

“I couldn’t inject, I couldn’t do anything.
So I was just hitting the gym real hard,” he toldFox News.
“The hardest thing with weight loss is maintaining that weight loss,” he said.

Claudia Oshry
Comedian Claudia Oshry is known for her unfiltered personality on social media.
She went on to disclose that she initially had reservations about using a drug to curb her appetite.
I have very mixed emotions.”

“I didn’t even know how different my life could be,” she said.
With some help from weight-loss drugs and the health platform Morph Wellness, she changed her physique.
“My body did not like it,” Chapman toldE!

Newsin 2024, recalling how Ozempic made her feel nauseous and totally ruined her appetite.
She found her magic bullet in tirzepatide, which helped her trim down to 126 pounds.
“I’m a binge eater.

“With an eating disorder, I have two voices in my head sometimes that argue.”
I did it to keep my emotions down, and to get numb,” she toldThe New Yorker.
“I’ve always been the funny fat guy.

Can I be the funny skinny guy?”
“I was really bummed out because it was working incredibly for me,” he said.
“You lose five pounds, people are nicer to you,” she toldPeople.

“I don’t know why.
It’s just the way the world works and that makes me sad for women.”
The Bravolebrity echoed this sentiment in a 2024 interview withABC News.

“I never realized how much my weight affected the way people treated me,” she said.
It changed my life.”
“It’s been a long, overdue glow-up.

“I’ve apologized for my body my entire life … and I’d rather just have body neutrality.
I love myself heavy.
I love myself now.”

“I was in a very, very dark place.
I just ate like sh**,” Moakler toldPeoplein 2024.
It was on another level, and I didn’t know how to deal.”

“I don’t think anyone has a clue about who I am,” she told People.
It’s like five to 10 pounds, which is so normal for a lot of girls.
She also revealed that she was dealing with an autoimmune disease and thyroid issues that affected her body.

“I had never experienced that kind of shame before.”
She turned to Mounjaro for help and help it did.
Not just with effectively managing her weight, but also by bringing other aspects of her health under control.

Hostin revealed that her weight gain triggered fluctuations in her cholesterol, causing it to shoot up to 200.
With medication, it was able to climb down 60 points.
Fat Joe
Fat Joe’s physical transformation counted among themost drastic weight loss transformations in 2024.

And yes, Ozempic played a key role along his weight-loss journey.
In 2000, Fat Joe’s friend, rapper Big Pun, died at the age of 28.
“I’m looking at his little daughter.

She was the same age as my daughter.
By 2024, he’d shed 200 pounds.
She also made certain lifestyle changes.

“I work out regularly.
“I better get back on it quick!”
She also told the outlet that she didn’t see harm in taking it.
“Many middle-aged woman, they benefit from this medication because it’s out of their control …
It’s our own misconception that we have of how somebody should look and what it means.”
“The same people that were commenting stuff like, ‘She looks like a skeleton.
“I can’t win.
And that’s okay because truthfully, I am happy.”
In October 2023, he took toInstagramto show off his costume.
“You are what you eat,” he quipped in the caption.
“Obviously, I didn’t look like this two months ago …
According to Underwood, she was inspired by her coworkers to make these moves.
Underwood was also motivated by the state of her own health.
She also noted that she even considered gastric bypass surgery at one point.
“I think I did my job because a lot of people were not being truthful about it.
“Having had a period of quite public self-destruction, I realised that that wasn’t working.
In recent years, George has turned to weight-loss drugs.
“Well, I’m on Mounjaro.
Trust me anyone who was fat last year and is now skinny is on the wonder drug.”
“Two months ago, my doctor put me on Mounjaro … and Repatha.
She shaved 10 pounds off her weight in a matter of weeks.
This is not the first time O’Donnell has made an effort to change her physique.
“Believe it or not, that surgery changed my life … “It’s been life-changing.
Josephs has been incredibly open about using drugs to help manage her weight.
She’s also shared that she hit a lot of roadblocks with every other health routine she tried out.
“I’d be working out, eating healthy, running around all the time and nothing …
I just wasn’t feeling my best self.
I was feeling tired and sluggish,” she recalled.
Peptides gave her, as she put it, “a new pep.”
“I really neglected myself those four months that we were filming,” she toldUs Weekly.
By the end of that year, Simpson had begun her Ozempic regimen.
If you need help with an eating disorder, or know someone who does, help is available.