The actor still often refers to the series as “life-changing.”

Unsurprisingly, she was never the same after the show wrapped.

Bialik revealed having undergone five stages of grief when the show ended.

Mayim Bialik smiling in a yellow dress at a press event

So instead, she went back to her hotel room, changed, and spent some time alone.

After saying goodbye to Amy, Bialik spent some time being a full-time mom.

After earning a PhD in neuroscience from UCLA in 2007, Bialik spent the next three years in academia.

Mayim Bialik posing at Moana premiere

She was married and had two children, so acting, at that point, was sidelined.

“I have a doctorate in neuroscience.

“I was cast, and literally, my life changed.”

Mayim Bialik posing with short hair at The Big Bang Theory press event

It caught her by surprise.

“I had, at that time, a toddler and a little older toddler.”

What initially was planned as a one-time appearance became a recurring role in Season 4.

The cast of The Big Bang Theory posing on Hollywood Boulevard

Amy also became one of the most loved characters as her bond with Sheldon deepened on the show.

According toThe Hollywood Reporter, the four-time Emmy nominee was reportedly paid over $425,000 per episode in 2017.

Even though Bialik already had an established acting career before playing Amy, the pay was unmatched.

Mayim Bialik at Barnes & Noble holding her book “Girling Up”

“It was just not on my radar.”

“I just finished nine years on a show that changed my life.

However, as a first-time celebrity, she had no idea what to do.

Mayim Bialik smiling at an interview

“I was clueless.”

She felt “distaste” for buying herself fancy things.

“I thought about the diamond industry and how I couldn’t support it,” she wrote.

Mayim Bialik giving a speech about science

The Big Bang Theory follows her everywhere she goes

Fame is a double-edged sword.

Bialik compared the show’s impact on her life to starting a new career.

There were a lot of celebratory moments, as well as some scares.

Mayim Bialik smiling next to Melissa Rauch

“I navigated everything with a lot of therapy and a good support system.”

“You couldn’t avoid seeing the show even if you didn’t want to,” she said.

“It was constantly on.”

Mayim Bialik smiling at a press event

To play Amy, she had to straighten her hair all the time, which left permanent damage.

“It stops about here,” she toldKara Mayer Robinsonin an interview, gesturing her chest.

“And it won’t grow anymore.”

Mayim Bialik attending a festival

Like Amy, Bialik grew up in a conservative family.

“I was a late bloomer and I play one on television,” she toldInsider.

Bialik’s scientific brain kicked in.

Mayim Bialik smiling in black glasses

“That’s not what I wanted to do.”

Can you yo put out a book?'”

She became a role model to aspiring scientists.

Mayim Bialik and Jonathan Cohen leaning toward each other

In 2021, she spoke at Penn State University.

In 2023, she guest lectured at Kent St. University.

“The Big Bang Theory” was the one thing that made it all possible.

“For me, coming from the world of academia…

The two even managed to drop a “The Big Bang Theory” Easter egg.

“You were in that?

I only remember the girl with the high voice.

She was great!”

Bialik is the third “The Big Bang Theory” actor to appear in “Night Court.”

Raj’s actor, Kunal Nayyar, previously appeared in Season 2 as a fashion designer.

Mayim Bialik hosted the puzzle show Jeopardy!

After “The Big Bang Theory,” Mayim Bialik joined the iconic puzzle show, “Jeopardy!”

In a joint “Jeopardy!”

It’s very stressful, sorry.”

She was certainly not alone in that experience: Jennings admitted that he even said his name wrong sometimes.

has a huge fan base and brought another level of exposure to Bialik.

She found herself at the center of criticism and controversy.

“Those things are in particular hurtful because they’re untrue.”

She was also accused of being anti-feminist for supporting breastfeeding.

“That’s just crazy,” the actor remarked.

Like many people, Bialik also had her doubts and questions about religion.

Her YouTube videos explain religious practice from a scientific perspective and what it means to her personally.

“An Orthodox Jewish woman who somehow found a way to make it in Hollywood?

It amazed the 18-year-old me,” wrote entertainment writer Adrianna Chaviva Freedman onForward.

“She shows that females can be successful in Hollywood without dressing and acting in a sexualized manner.

Bialik made her directorial debut.

In an interview withVariety, the star revealed the idea came to her whenshe experienced a tragic lossin 2015.

“I started writing prose.

It wasn’t even in screenplay format.”

The film was released in 2022.

“It took a lot of labor and a lot of love to pull it together.

It’s still very surreal.”

But “Mayim Bialik’s Breakdown” isn’t just about sharing her stories.

She debunked the myth of the systemic belief that people don’t believe in getting help in that interview.