With that said, he’s experienced a great deal of hardship.

Fame may have brought him professional highs, but it has also exposed him to profound personal losses.

These friendships, much like family relationships, bring heartache when tragedy strikes.

Dennis Quaid smiling

He also reminisced about the joy Richardson brought to set.

“She always had a smile on her face when she came to work,” he said.

“That really affected everyone around her.”

Dennis Quaid and Natasha Richardson smiling

Over a decade later, her loss remains a tender wound for the actor.

“He had such a great heart.

He was such a talented actor too and he had a thirst to learn.”

Tupac Shakur black hat

When Shakur was shot in 1996 and died shortly after, Quaid was deeply affected.

“That one really hit me,” he admitted.

“It really did.”

Dennis Quaid the substance event

His experiences with addiction

Dennis Quaid’s experience with addiction was one that nearly cost him everything.

“I was in a band, and we got a record gig … Now, after years of sobriety, Quaid is able to reflect on his journey with gratitude and clarity.

Yet the legacy of William Quaid lives on in his son’s ongoing dedication to his craft and family.

Dennis Quaid staring ahead smiling

It was the same number of days.

In that night I was older than my dad had been.”

The loss undoubtedly shaped him, and Quaid still feels it to this day in one way or another.

Dennis Quaid and Kimberly Buffington

“The danger would be rupturing an artery.

And they were so small they couldn’t thrash around.

I think that’s what saved them.”

But the story didn’t end there.

If you or anyone you know needs help with addiction issues, help is available.

Visit theSubstance Abuse and Mental Health Services Administration websiteor contact SAMHSA’s National Helpline at 1-800-662-HELP (4357).