Her performances have earned her numerous accolades, including Emmy and Tony Award nominations.

Fans most recently saw her in the Netflix comedy “Dead To Me.”

However, it’s unlikely Applegate will return if the show comes back for another season.

Christina Applegate at Walk Of Fame

Applegate has faced a string of health strugglesover the years, beginning with a 2008 breast cancer diagnosis.

This led her to undergo a double mastectomy.

The disease, which affects the central nervous system, has left Applegate forced to walk with a cane.

Christina Applegate at an event

As her condition progresses, Applegate is making plans for her future away from the camera.

“I can’t even imagine going to set right now.

This is a progressive disease.

Christina Applegate at an event

I don’t know if I’m going to get worse,” Applegate added to Vanity Fair.

Even with multiple sclerosis, she is still eager to make a living for herself.

Applegate detailed her future plans in a February 2023 chat with theLos Angeles Times.

This is undoubtedly a lane that Applegate is familiar with.

Even though Applegate is stepping away from the spotlight, she remains a well-respected figure in the entertainment industry.

No matter which path Applegate chooses to take moving forward, her peers undeniably love the star.